Lipomatosis of the pancreas is called an irreversible process in which the cells of this organ undergo pathological changes and, in fact, are replaced by cells of adipose tissue. After such changes, the pancreas can no longer work as before, since new cells (fat cells) cannot perform those functions that are performed by pancreatic cells. In a different way, this pathology is called fatty dystrophy (steatosis) of the pancreas.
Lipomatosis occurs when the cells of the gland itself die due to some factors, such as inflammation. In order to maintain the shape of the body, its integrity, the body begins to produce a certain type of cells that would play this role. Thus, a defensive reaction occurs which, unfortunately, does not add health to the organ. Pancreatic cells that are dead are replaced by either connective tissue or fatty inclusions. It is worth noting that not all the pathologies of the pancreas can cause lipomatosis. Neither one nor the other cell type can function as a pancreatic cell in its structure, but without their presence, full-fledged work is also impossible. If such inclusions are small, then a person with such cells can live a lifetime without experiencing any discomfort. But sometimes the process ceases to be controlled by the body, and fat cells begin to grow unnecessarily, forming whole fatty islets.
Often, the pancreatic lipomatosis can proceed for a long time without any obvious symptoms that would force one to go to a medical institution. This is especially the case when fatty inclusions are located in small foci, as if scattered around the pancreas. Such diffuse inclusions do not squeeze pancreatic tissue and do not interfere with the basic functions. Most often, lipomatosis is detected by ultrasound, when a patient comes to a medical institution on a completely different matter.
On ultrasound examination assess the overall condition of the gland, its visual parameters. An increase in its individual parts may indicate various pathologies that may cause necrosis and subsequent complications such as lipomatosis, therefore, at this stage, the patient should pay attention to this organ. If the fatty blotches are already present, then it is shown by the echoes of the apparatus, which are distributed unevenly throughout the gland, thus making the diagnostician understand where the pancreas is affected and how large the foci are in size.
Lipomatosis of the pancreas is a benign disease and, provided that the diet is observed, does not pose a serious threat to the life of the patient. The disease progresses slowly.
Lipomatosis is ...
In medicine, lipomatosis refers to a condition in which pancreatic cells undergo pathological processes, as a result of which they are replaced by adipose or connective tissue. This process is not reversible. If it began to develop, it becomes impossible to restore the functioning of the cells, which means that after the onset of this disease, the pancreas will never work as before. This is due to the fact that fat cells can not function the way pancreatic cells did.
Lipomatosis has several other names - fatty lipomatosis, steatosis, fibrolimatosis, hepatosis. The main cause of its occurrence is pancreatic cell death. As a rule, this phenomenon occurs with the development of acute or prolonged chronic diseases, for example, pancreatitis or pancreatic necrosis. And to preserve its integrity, the iron begins to produce cells, which are the so-called building material for it.
Thus, it turns out that lipomatosis is a natural protective reaction of the body, which, unfortunately, does not add health, but on the contrary, takes it away. Instead of healthy and functioning cells in the pancreas begin to dominate fat or connective inclusions. However, neither of them can perform functions, and therefore the work of the gland is disturbed.
The causes of pancreatic lipomatosis have not yet been established. However, according to scientists, if lipomas form in other internal organs, the risk of their occurrence in the gland increases several times.
In parallel with this, doctors isolate diseases that are usually diagnosed:
- alcohol and nicotine addiction,
- chronic pancreatitis,
- type 1 and type 2 diabetes
- hepatitis, in which liver function is impaired,
- hypothyroidism characterized by insufficient synthesis of thyroid hormones.
Scientists suggest that the above somatic diseases can not only provoke pancreatic lipoma, but also be a consequence of this disease. Therefore, if a person has been diagnosed with this disease, it is necessary for him to undergo prophylactic examinations from time to time in order to promptly identify complications and begin their treatment.
With the development of pancreatic lipomatosis, the symptoms may be different. It all depends on the course of the disease and the degree of organ damage. If fatty and connective inclusions are small in size and evenly dispersed throughout the gland, then in this case there are no symptoms that would cause a person to see a doctor. Small diffuse changes do not exert pressure on the parenchyma of the organ, therefore, do not interfere with its normal functioning. In this case, the detection of pathology occurs completely by chance during the passage of an ultrasound for another disease.
As a rule, during an ultrasound examination, the doctor assesses the overall state of the pancreas, comparing its size with normal values. If some of its areas have seals, this already indicates the development of certain diseases that can lead to necrosis or lipomatosis. Therefore, when detecting even minor deviations from the norm during an ultrasound, the patient needs to pay attention to this body and undergo a more detailed examination, which will allow to establish the exact cause of such changes.
In the event that the organ already has inclusions by type of adipose tissue, the echogenicity of the organ (its ability to reflect ultrasonic waves) “tells” this. It becomes uneven, which allows us to understand exactly which parts of the pancreas underwent pathological processes.
If the fat inclusions are large, then this leads to serious changes in the work of the pancreas, which is manifested by various signs:
- increased blood sugar
- bowel disorders
- pains in the left or right hypochondrium,
- aversion to fatty foods
- drastic weight loss
- high fat content in feces,
- the presence of undigested food pieces in fecal masses, etc.
The degree of development of pancreatic lipomatosis
Speaking about the stages of development of pancreatic lipomatosis, it should be noted that in this case, experts' opinions differ slightly, although each statement has its right to life. If we consider this disease on the part of the prevalence of pathological processes, then in this case the disease has three stages of its development. Lipomatosis of the pancreas of the 1 st degree is characterized by a lesion of no more than 30% of the cells of the organ, 2 degrees - from 30% to 60%, 3 degrees - more than 60%.
But there is another opinion. If, for example, a person has a focal lipoma that affects certain parts of the pancreas, for example, near-flow zones, then the organ’s functionality is significantly reduced, although in terms of the prevalence of pathology it may fall into the first stage, with the development of which or signs of illness.
And when the ducts are squeezed, it causes serious digestive disorders, which can manifest nausea, diarrhea, colic and other symptoms. And in general, the general condition of the patient is deteriorating, which affects its performance and leads to increased fatigue.
But there is another group of specialists who classify pancreatic lipomatosis as follows:
- small focal or diffuse,
- merged, in which fatty “islands” appear on the organ.
Treatment of pancreatic lipomatosis can occur in several ways:
Medical therapy with medicines is indicated if the fatty inclusions in the pancreas are small in size and are of a disseminated type, that is, they are evenly distributed throughout the gland and do not interfere with its functioning. But if the fatty inclusions merge to form "islands", squeeze the pancreatic ducts and cause a violation of its functionality, then surgical therapy is indicated in which the pathological lesions are removed.
As for conservative treatment, it includes:
- a diet whose main purpose is to reduce fat intake,
- getting rid of excess weight.
Nutrition for pancreatic lipomatosis
A diet in pancreatic limopathis is one of the most important and key points in the treatment of this pathology. Since it is accompanied by irreversible processes in the pancreas, to eliminate the affected areas will not work. Therefore, the main goal of therapy is to halt the development of pathological processes. And this can help only proper nutrition. It will prevent the progression of the disease and avoid the occurrence of complications for which an operation will have to be performed.
The basis of the diet is fractional nutrition. Although it is the principle of proper nutrition, in modern society it is perceived as a kind of exception or coercion, but this is not the case now. So, a patient who has been diagnosed with lipomatosis should be eaten up to 5 times a day in small portions.
As for the food itself, in this case, treatment table No. 5 is appointed, which in principle is shown to all people suffering from pancreatic diseases. It has some dietary restrictions, which suggest the exclusion of the following products from the daily diet:
- fatty and fried foods,
- sweet baking,
- smoked meat
- semi-finished products
- canned food
- fast food,
- carbonated and alcoholic beverages,
Medical table number 5 is good because it has lipotropic properties, prevents further weight gain and at the same time provides the human body with all the necessary nutrients. But in order for food to be consumed to really benefit and prevent the further development of lipomatosis, it must be prepared according to certain rules. All dishes should be cooked, stewed without adding oil, or steamed. But it is better to use dishes in the wiped and warm form.
Hot, cold and whole lumpy dishes are contraindicated in this disease, as they irritate the pancreatic mucous membranes and increase the production of digestive enzymes, which puts additional pressure on it and can lead to the progression of pathological processes in it.
Meat dishes (meatballs, meatballs, dumplings, etc.) are not contraindicated for patients, but they should be cooked only from lean meats such as chicken, veal, rabbit meat, etc. The same goes for fish dishes. However, the main part of the diet should be vegetables, namely:
Also required is the use of cereals - buckwheat, oatmeal, rice. They contain a lot of nutrients that are required by the body for normal functioning. Milk and dairy products (kefir, sour cream, cottage cheese, etc.) should also be in the patient's daily diet, but before they are consumed, you should carefully watch the fat percentage of the product. It should not exceed 2.5%.
Therapeutic table number 5 is very diverse. It does not make a person starve or experience a constant feeling of hunger. As practice shows, the most difficult days for patients are the first 3-4 days of dieting. Then their body gets used to the new regime and nutrition, after which no discomfort is experienced.
Lipomatosis of the pancreas is a serious disease. And his treatment should be approached with the utmost responsibility. If the patient strictly follows the dietary rules, the presence of this disease will not affect his general well-being and quality of life. But if he continues to eat improperly, this will cause the progression of the disease and can lead to serious consequences.
Classification of pathology
In gastroenterology, pancreatic lipomatosis is classified according to the degree (stage) of dystrophy and the forms of tissue damage.
Classification by degrees:
- Grade 1 - fatty dystrophy is poorly developed, fat cells are replaced by up to 30% of the total volume of the organ, pathology with grade 1 occurs without obvious symptoms and is often detected by chance, during ultrasound of the abdominal organs,
- Grade 2 - cells of the fat depot make up 60% of the volume of the organ, the pancreas is not able to fully secrete digestive enzymes (amylase, trypsin, lipase), so the clinical picture becomes more pronounced,
- Grade 3 - extensive degeneration of the tissues of the organ, the cells of the fat depot constitute more than 60% of the glandular volume, the digestive functionality is reduced to a minimum - the production of enzymes is practically absent, insulin production is disturbed, the whole body suffers.
The classification of pathology by forms is based on the localization of fat cells in the pancreas. Their accumulation can be local or generalized. From this position, the forms of lipomatosis are distinguished:
- knotty - it is typical for the formation of single cells of the fat depot in the stroma of the pancreas,
- diffuse - fatty nodes are multiple, are located in the stroma and the paematomial layer chaotically, without a specific sequence, with a duffus lesion, the lesions of the accumulation of fat cells are blurred, do not have clear boundaries,
- mixed form - the defeat of the pancreas, represented by single nodes and large areas of fat "islets".
Sometimes in the process of degeneration of the pancreas foci of fat and connective tissue are formed. When running, detect areas of dense scar tissue. This condition is called fibrolipomatosis - a special form of pathology that occurs on the background of chronic pancreatitis.
The course of fibrolipomatosis is severe - the pancreas increases in size, squeezing the adjacent organs, in the painematous layer forms a lot of fibrous nodes and seals. The treatment is exclusively surgical.
Lipomatosis of the pancreas is often hidden, especially at the first stage in combination with the nodular form. Single lipomas do not cause serious problems with splitting of food and do not create discomfort for the patient. Clinical manifestations become palpable in stage 2 with more extensive tissue degeneration - dyspepsia develops with characteristic manifestations:
- mild pain in the left hypochondrium and in the center of the abdomen, sometimes the pain intensifies at night,
- Increased flatulence due to inadequate digestion of food - its remnants begin to ferment in the large intestine, causing bloating, flatulence,
- belching with an unpleasant odor after eating,
- mild nausea after eating.
As the disease progresses, symptoms include not only dyspeptic symptoms, but also a picture of the endocrine system disorder (diabetes):
- pain in the abdomen becomes regular,
- there is a disorder in the stool - constipation gives way to diarrhea, drops of fat can be seen in the stools,
- often vomiting occurs after eating,
- integuments lose elasticity, become dry,
- there is a feeling of constant thirst
- appetite increases, against the background of this patient is gaining deprivation of kilograms,
- dysuric disorders appear.
Signs of diabetes mellitus on the background of lipomatosis are due to a decrease in the organ's intrasecretory function — in the case of fatty degeneration, insulin and glucagon secretion is insufficient. There is a shortage of insulin, with long-term lack of it develops diabetes.
Diagnosis of pancreatic lipomatosis includes an ultrasound of the abdominal organs. When echography visible structure of the tissues of the body with increased echogenicity, the presence of atypical foci in the form of fat "islands". According to the results of ultrasound, it is possible to reliably establish the degree and form of pancreatic damage.
If there are doubts in the structure of atypical areas of the gland, the doctor performed the ultrasound diagnostics, a biopsy is performed followed by a morphological study of the taken tissues. A biopsy for 100% will confirm the presence of lipomatosis - in case of fatty degeneration, the material will consist entirely of pathological cells of the fat depot.
Treatment of lipomatosis is reduced to preventing the progression of pathology and restraining the growth of fat cells. It is impossible to fully restore the pancreas and its tissue by either medication or surgical intervention. Treatment of steatosis includes conservative methods aimed at maintaining the secretory function of the body. In case of advanced course (stage 3 with extensive diffuse tissue degeneration), operations are performed (excision of degeneration foci).
The first and second stages of lipomatosis require the appointment of conservative replacement therapy:
- strict diet to prevent obesity and further fat deposition in pancreatic tissue,
- course treatment with pancreatin-containing drugs (Festal, Creon, Pangrol) to restore adequate digestion and hormone deficiency,
- use of antispasmodics to relieve pain (Buscopan, Drotaverin, Baralgin),
- taking medication to relieve dyspeptic symptoms - Loperamide for diarrhea, Zerukal and Domperidone for nausea, vomiting,
- avoiding bad habits and maintaining a healthy lifestyle.
Nutrition Features of Patients
The diet in pancreatic lipomatosis is of paramount importance in restraining the process of degeneration of the organ. Properly organized food reduces the load on the gland, allowing it to function calmly, without failures. The basic dietary principle is fractional and frequent meals, up to 5–6 meals per day. Ideal for people suffering from fatty dystrophy is the table number 5, designed by Pevsner specifically for people with lesions of the digestive tract.
The main rules on nutrition for patients with lipomatosis:
- reducing the amount of fat in the diet while maintaining an adequate amount of protein and carbohydrate foods,
- complete elimination of salty, roasted, sweet and spicy,
- rejection of products with coarse fiber and a high content of extractive substances,
- Preferred cooking methods are boiling, stewing, baking, stewing.
For patients with steatosis, daily calorie content is limited, but it is not recommended to reduce the total calorie volume below 2800. The basis of the diet consists of dishes from lean meat, white fish, dairy products with a low percentage of fat, cereals in the form of buckwheat and oatmeal. Diet does not prohibit the use of vegetables - zucchini, potatoes, pumpkins and carrots.
Lipomatosis is not considered a life-threatening pathology, but control over the state of the pancreas requires constant. Traditional medicine offers to treat steatosis with herbal medicine. Infusions and decoctions of healing herbs will help to slow down the growth of adipose tissue and partially restore the pancreatic secretory abilities.
It is important to clarify - before using traditional recipes, you need to contact your doctor. The specialist will take into account the general condition of the patient, weigh the benefits and the possible risk of herbal medicine. Additionally, you must ensure that there are no allergic reactions to the constituent components of herbal teas.
Popular folk recipes for pancreatic fatty degeneration:
- decoction of purified oats helps to establish metabolic processes in the body, improve secretory function, drink broth instead of tea 400 ml per day,
- The infusion of blueberry leaf is useful for lipomatosis in the initial stages, they are drunk 100 ml each morning and evening before meals,
- regular consumption of fresh cranberries can prevent further formation of wen in the pancreas,
- A decoction of blackberry leaves is drunk for a long time with a diffuse lesion of the gland, they take 20–30 ml per day up to 4 times a day,
- Herbal infusion of nettle leaves, valerian root, marigold and St. John's wort is taken in courses for 3 weeks with a 7-day break for a long time, up to 250 ml should be drunk per day,
- In addition to herbal treatment, mummy is used - a powerful natural stimulant, with uncomplicated steatosis, oral mummy 20 mg twice a day for 14 days will help restore the pancreas.
Compliance with basic preventive measures helps to reduce the likelihood of pancreatic steatosis by 80%. Effective preventive measures include:
- control of normal weight, preventing the development of obesity,
- healthy, carefully balanced diet,
- quitting smoking and drinking alcohol
- adequate physical activity
- preventive medical examinations and timely treatment of the detected ailments (especially those related to the dysfunction of the pancreas, liver and endocrine system).
Anyone can prevent the development of pancreatic steatosis, and treatment of an already confirmed disease will take a long period. The disease often manifests itself in advanced stages, when it is difficult to do without surgical intervention. Therefore, it is important for any warning signs on the part of the digestive tract and pancreas (pain, nausea, problems with appetite, weight gain) to consult a gastroenterologist for qualified help.
Extent of the problem
The disease has three phases of gland damage. At the beginning of the formation of inflammation, a change in the number of healthy cells occurs - about a third of them are replaced by the fatty layer. Lipomatosis at this stage of progression occurs without marked signs.
When transforming into the second phase of pathology, dystrophic changes occur inside the pancreas - the replacement of half of this organ by fat cells. The patient has the following manifestations of lipomatosis:
- frequent nausea
- long burp episodes,
- sensations of pain in the peritoneum.
At the last stage, the disease is characterized by an even greater capture of healthy gland tissue. Diffuse changes observed in the pancreas in a situation with lipomatoz, cause dysfunction of the digestive system.
Important! At this phase, lipomatosis ceases to produce insulin, which adversely affects the metabolic processes. In the presence of progression of pancreatic disease, there is a risk of transforming a benign lesion into oncology.
According to the type of damage to the pancreatic cells, the lipomatosis itself is classified as follows:
- small focal or diffuse type of lipomatosis in the pancreas.
To stop the process of lipomatosis in the pancreas, the following popular recipes should be used:
- Hemlock tincture. Gland therapy regimen: 1 drop per day at the start of treatment. If there is no allergy, the dosage can be increased to 40 drops.
- Herbal collection. It is prepared on the basis of calendula, fresh valerian, nettle leaves, and Hypericum flowers. Herbs are taken in equal proportions. 1 tbsp. l collection pour a glass of boiling water and insist to cool. Take need for 1 tbsp. l up to 4 times a day.
- A pinch of dry wormwood will also help remove an unpleasant picture. The drug should be consumed before meals.
- A decoction of wheat. The ingredient needs to be washed, chopped and boiled for about 15 minutes in 4 cups of water. Medicine insist 60 minutes, take 0.5 cups before meals three times a day.
Diet is a crucial stage in the treatment of lipomatosis and other problems with the pancreas. In order to prevent the growth of fat and improve overall health, you must follow the diet number 5. It is necessary to eat often and in small portions, eating about 5 times a day.
- smoked meat
- fried, spicy or fatty dishes,
- any nuts,
- sweet soda.
Food is recommended to cook only a couple. For the garnish one should prefer:
- baked pumpkin,
- Brussels sprouts
- vegetable salads.
It is also recommended to include in the menu:
- dairy products
- porridge from buckwheat, oats, millet,
- lean fish
Degree of pancreatic lipomatosis
If we talk about the degrees of lipomatosis, here the opinions of clinicians are somewhat different, although each theory has its own right to life. If we take as a criterion the extent of the pathological process, then the pancreatic lipomatosis is divided into three degrees - the first (with an insignificant liver damage up to thirty percent of the total organ area), the second degree (from thirty to sixty percent) and more than sixty percent - the third degree. However, another group of researchers rightly noted that a focal lipoma localized in a certain area (for example, near the ducts) significantly reduces the quality of the organ, although according to the classification it may well fall under the first degree, in which most patients do not even show symptoms. But when the ducts are squeezed, severe dysfunctional disorders of the digestive organs occur, which react with nausea, heaviness in the stomach, colic, flatulence, diarrhea and other symptoms. Patients generally feel decreased performance and increased fatigue. In turn, another group of doctors identifies both small-focal (diffuse) lipomatosis and fusion (islet, when fat cells merge into one large spots) as stages.
Lipomatosis can be treated either conservatively or surgically. Conservative therapy is possible only when the fat inclusions are small, scattered throughout the pancreas or a small part of it does not squeeze its ducts. If the fat cells merge into one large islets, squeeze the ducts of the gland and prevent the outflow of secretions, then surgical intervention is necessary - removal of lipomatous nodes.
The essence of conservative therapy lies in several major events:
- strict diet to limit fat intake
- decrease in overweight, if any (according to statistics, the majority of people suffering from pancreatic lipomatosis are overweight) - this measure will help partially remove fat from the lipid depot in the pancreas,
Since lipomatosis is irreversible, that is, it is already impossible to cure the affected areas, the main goal in therapy is to stop the further spread of fatty inclusions. At this stage, diet is of paramount importance, since it is the right diet that is strictly followed by the patient can prevent surgery if the process begins to progress.
The basis of the diet - fractional nutrition. In principle, this is not so much the basis of the diet, as a rigorous algorithm of proper nutrition in principle, but in modern conditions even this rule is perceived as an exception. So, you need to eat four or preferably five times a day. Diet for pancreatic lipomatosis is widely based on the table number 5, which is shown to all patients with diseases of the digestive tract. Patients should be excluded from the diet fried foods, pickles and smoked, spicy and fatty foods, sweets, baking, chocolate, alcohol.
Table No. 5 is in all respects good for patients with lipomatosis - it is it that has lipotropic properties, inhibits the process of obesity, provides the body with a significant amount of easily digestible food, which is perfectly digested both by the stomach and intestines.
In order for food to be gentle, it is recommended to be steamed - this eliminates the addition of oil, which is desirable to minimize in patients. Meat dishes are best prepared from low-fat poultry meat, fish, and replace, if possible, with vegetables — pumpkin, zucchini, cauliflower, potatoes.
Mandatory in the diet is the use of cereals - buckwheat, rice, oatmeal, which provide the body with essential trace elements. Also, patients should be sufficiently consumed dairy dishes - include in the composition of the first courses (sour cream), salads (sour cream, kefir), pastries (cottage cheese casserole).
In general, the diet of a person suffering from a similar disease should be compensated and have no less than 2800 calories per day.
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Causes of the disease
In inflammatory, infectious processes in the pancreas, tissue disintegration and necrosis occurs in certain areas. If treatment was carried out on time and fully, the growth of pathogenic microflora is stopped and the organ restores its work. On the site of the damaged areas, new ones are being formed. Often this is the filling of the resulting lumen with fatty tissue. That is, lipomas are formed (Wen). In most cases, the inflammatory process in the organ (pancreatitis) becomes the impetus for the formation of lipomas in the pancreas. It causes damage and destruction of cellular structures of the pancreas. Gradually, their replacement with adipose tissue.
Factors contributing to the development of lipoma:
- genetic predisposition
- chronic liver disease, hepatitis,
- alcohol abuse
- abdominal injuries,
- the use of drugs that destroy the cells of the pancreas,
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For a very long time, the pancreatic lipoma does not manifest itself. The process is developing slowly over the years. Fatty dystrophy is often detected by chance during an ultrasound scan. Primary signs of fatty dystrophy are not significant and they are often not paid attention to. Their severity is directly dependent on the size and degree of substitution of healthy adipose tissue. If less than 30% of the organ is affected, then the patient may hardly feel the change.
Symptoms of pancreatic lipoma:
- pain in the left hypochondrium, the epigastric region,
- feeling heavy after eating,
- impaired intestinal motility,
- steatorrhea (fat in feces),
- nausea, vomiting,
- general malaise,
- loss of appetite,
Disruption of carbohydrate metabolism is observed with increasing glucose levels due to a decrease in insulin synthesis. As the fatty tumor grows, it begins to put pressure on the ducts of the gland, blood vessels, and nerve fibers. As a consequence, a number of associated symptoms may appear.
Although the pancreatic lipoma is not classified as a dangerous pathology, but it constantly progresses and leads to significant organ dysfunction. Therefore, early diagnosis of changes and treatment of lipomas are very important. Based on the stage and severity, conservative or surgical treatment may be proposed.
In diffuse lipomas, a therapeutic diet and taking certain groups of drugs are recommended. Correction of nutrition is necessary to relieve the load from the affected organ, providing the body with all nutrients.
In case of problems with the pancreas, food close to table No. 5 is recommended. Diet involves a complete rejection of fatty, fried, spicy, salty foods. You can not drink alcohol, coffee, chocolate, baking. Meals should be steamed or boiled. Eating should be in small portions 5-6 times a day. When lipoma is useful to use buckwheat, rice, oatmeal, pumpkin, cabbage, dairy products.
There are no specific drugs that can cure lipomatosis. Medicines are prescribed by a doctor to relieve the symptoms of the disease:
- antispasmodics (Drotaverine, No-shpa),
- antidiarrheal drugs (loperamide),
- enzymes (Festal, Creon),
- in case of insulin synthesis deficiency, its synthetic analogues.
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The operation can be prescribed in the event that the size of the lipoma reaches a large size, exert pressure on the nearest organs. Surgical removal of a lipoma in the insular form of pathology is shown. It is assumed the excision of non-functional areas of the pancreas, in some cases, the body is removed completely. With complete pancreatic ectomy, a lifelong reception of pancreatic enzymes and the introduction of insulin injections as replacement therapy are subsequently prescribed.
What is pancreatic lipomatosis?
The pancreas plays an important role in the body in the production of enzymes necessary for carrying out metabolic processes. As the cells of this organ atrophy, their productivity decreases markedly. Usually this happens gradually and does not cause any special changes in state of health. But due to some factors contributing to the acceleration of these irreversible actions, such disorders in the state of the gland occur so rapidly that by the age of 30 or 40, it consists of more than sixty percent of adipose tissue. The performance of this body is also reduced so much that it is not able to produce a sufficient amount of enzymes, as a result, this affects the entire metabolism. Due to the lack of nutrients in the body, the immune system and the functions of many organs and systems suffer.
With advanced stages of the disease, it is not possible to fully restore the state of the pancreas and the likelihood of an unfavorable outcome with a lethal end is more than likely in such cases. The only thing that should be done in such a case is to suspend the atrophic processes in the gland cells, which will slow down the irreversible degeneration of its cells into fat. Since the initial stages are usually asymptomatic, such patients usually come to doctors with extensive lesions, when the percentage of fat in their pancreas reaches forty or more. The danger is that such violations can spread to nearby organs, often with steatosis accompanied by liver lipomatosis.
Lipomatosis of the pancreas of the first degree
Lipomatosis is able to have various stages of lesions occurring in the pancreas. The first degree is characterized by a practically asymptomatic course, which are either completely absent or expressed so weakly that they are perceived as a usual malaise. Rebirth of the cells of the body in the adipose tissue takes no more than thirty percent of its volume, and there is still no change in the functionality of the pancreas.
Often, this disease in its initial stage is detected by chance during an ultrasound scan when examining organs located in the abdominal cavity.
Causes of lipomatosis
The reasons for the development of lipoactosis are not fully elucidated, only a mutual connection between the existing wen in the subcutaneous layer and in adjacent organs and the lipomatosis in the pancreas has been revealed. Not the last significance in the occurrence of disorders in this organ has a genetic predisposition, in one whose close relatives had the same disease, pancreatic steatosis occurs one and a half times more often.
There are also other reasons under the action of which lipomatosis can develop, namely:
- Excess weight,
- Available bad habits in the form of alcohol abuse and smoking,
- Chronic pancreatic diseases
- Acute diseases and infections of the pancreas,
- Pathology of the endocrine system in the form of diabetes or gipoterioz,
- Oncology affecting the airways
- Slow metabolism
Older age also contributes to the degeneration of liver tissue, this often occurs in people over the age of 70 years.
Types of pancreatic lipomatosis
In medicine, lipomatosis in the pancreas is classified according to the stage of dystrophy and the form in which organ tissue damage occurs. The classification according to the forms is based on the location of the accumulations of fat cells in the pancreas:
- Nodular form - a few cells of fat are formed in the stroma of the body.
- Diffuse form - the appearance of a large number of fatty nodes, which are able to form in the stroma and the paine-mathematics part. They are arranged in a chaotic manner, without consistency and without limitation to a clear boundary.
- Mixed form - own gland tissues are replaced by different in size fatty areas.
Lipomatosis is classified due to the varying degree of dystrophy that has occurred in pancreatic tissues, as follows:
- The first degree is characterized by mild changes in the state of the organ, fat cells occupy no more than 30 percent of the total.
- The second degree, in which adipose tissue is able to make up 60 percent of the total area, the pancreas becomes unable to fully perform its assigned functions with the release of digestive enzymes. Clinical indicators are becoming more pronounced.
- The third degree manifests itself by extensive tissue degeneration, with the content of fat cells up to 60 percent or more. Functions of production of enzymes for digestion are practically absent, insulin is not produced.
Often, when changes occur in the pancreas, not only fat and connective tissues are formed in it, but also areas formed from dense scar tissue. They are the result of chronic pancreatitis and are called fibrolipomatosis.
Symptoms of lipomatosis
Lipomatosis usually proceeds covertly, which is especially characteristic of the nodular form in the initial stage. Solitary lipomas are not accompanied by a disorder in the breakdown of food and do not cause discomfort in patients. Clinically tangible signs of the disease become only after reaching the disease of its second stage with a more extensive prevalence of adipose tissue. In this state, symptoms of dyspepsia develop with manifestations corresponding to this stage:
- There are mild pains in the left side and in the central part of the abdomen, which can intensify at night,
- The patient is concerned about increased gas formation caused by insufficient digestion of food with the resulting fermentation processes in the intestine,
- After a meal, an unpleasant belching occurs,
- Patients may experience nausea.
As the disease continues to develop, its manifestations are expressed not only by dyspepsia. A clinical picture of the disease can be supplemented by disorders in the endocrine system in the form of diabetes, as well as the appearance of other, pronounced symptoms:
- Constant feeling of pain in the abdomen,
- There are visible disorders of the stool with a change of constipation for diarrhea, and in the fecal masses particles of fat are found,
- After eating, vomiting may occur,
- There is a change in the condition of the skin, it becomes dry and inelastic,
- Worried about the constant presence of thirst,
- Usually, patients quickly become overweight due to increasing appetite,
- In the body, there are dysuric disorders in the process of urination.
Symptoms, corresponding to the development of diabetes mellitus in the presence of lipomatosis, occur due to reduced organ secretion with insufficient production of insulin and glucagon. Prolonged insulin deficiency leads to diabetes.
Diagnosis of lipomatosis
When conducting a diagnosis, the examination of the patient reveals the following:
- Seal in the form of a lipoma is located in areas with accumulation of fatty tissues,
- This tumor is painless, mobile when probing,
- To the touch is soft, and when stretching the skin over it, there is their characteristic retraction.
To conduct an accurate diagnosis, a study is conducted using ultrasound, which allows to determine the lesions with accumulations of adipose tissue. X-rays reveal foci of enlightenment, in some cases, using X-rays with contrast. Rather widely in the diagnosis of lipomatosis and related diseases, computed tomography and MRI are used. During the examination, it is possible to identify lesions that are atypical for the gland as accumulations of fat and determine the extent of the lesion and its shape.
In case of doubts in the state of the pancreas, a biopsy is performed with a study of the tissue samples taken. This allows one to confirm the existing lipomatosis by the presence of a large number of fat cells in the analysis with an accuracy of one hundred percent.
Treatment of lipomatosis in the pancreas
After the diagnosis on the basis of the results obtained, the necessary treatment is carried out, which is reduced to suspending the further progression of pathological changes and restraining the proliferation of fat cells. Restoration of the tissue in the original state is impossible, and it can not be done either with the help of operational methods or with the help of therapy. Treatment involves only conservative methods that contribute to the maintenance of the organ's secretory functions. Only in the case of the advanced stage of the disease with the observed extensive degeneration of tissue into fat, an operative excision of the lesions with dystrophy is carried out.
The onset of the disease in the form of stages 1 and 2 of lipomatosis is followed by treatment with the help of replacement therapy:
- The use of drugs with the content of pancreatin in them, which allows to compensate for the lack of hormones and restore normal digestion.
- Strict diet will be required to prevent further production of fat cells and their deposition in the pancreas.
- The appointment of antispasmodics to eliminate pain symptoms in case of their occurrence.
- Elimination of dyspepsia symptoms with medications.
It is necessary to abandon habits that irritate the pancreas. This primarily refers to the use of alcoholic beverages. Maintaining a healthy lifestyle is also an important point in the treatment of disorders in the condition of this organ.
Treatment of folk remedies of pancreatic lipomatosis
Lipomatosis is not a direct threat to the lives of patients with the presence of this kind of pathology, but since this disease tends to progress, it is necessary to constantly monitor the condition of this organ and, if necessary, take appropriate measures. In addition to the methods of official therapy, there are many recipes of traditional medicine that can stop the growth of adipose tissue in the pancreas and partially return it to its secretory capacity.
Before conducting this kind of treatment, it is important to discuss it in advance with your doctor, who, on the basis of the patient’s general condition, will assess the possible risk of treatment with herbal remedies and the benefits they may bring. As the most popular folk remedies for the treatment of fatty degeneration of the pancreas use:
- Broths of oats grains that can lead to normal metabolic processes and improve the secretion of the gland,
- An infusion made from bilberry leaf will benefit from the initial stages of lipomatosis,
- The use of cranberries will not allow the formation of new wen
- Blackberry leaf decoction is useful in the diffuse form of the disease,
- The collection of nettle leaf, calendula, St. John's wort and valerian root helps to improve the state of the pancreas,
In addition to medicinal fees from plants, the treatment of bee products with lipomatosis is very helpful, in particular, the use of such a natural immunostimulant such as mummy. Its use for two weeks at the initial stage of lipomatosis is able to restore pancreatic function.
Life expectancy for pancreatic lipomatosis
Lipomatosis of the pancreas is not a sentence, with an adequate perception of this change in the state of this organ and the right lifestyle, it compensates for its missing capabilities. Healthy cells begin to secrete the amount of enzymes that is necessary for full-fledged metabolic processes.
With careful attention to their disease, long-term remission is possible, ensuring good health and preventing the replacement of healthy cells with fat.
If the fatty dystrophy of the pancreas is not conducive to the creation of favorable conditions for this organ, then several new ones in the form of diabetes, serious digestive disorders, pathological changes in the liver and intestines, as well as general intoxication of the body, can be added to the existing problem.
Patients with the presence of lipomatosis need to remember that this disease is chronic and albeit slowly, but steadily progressive. The task of physicians is to halt its development and cause persistent long-term remission.
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With the passage of medical examinations at work, most of the team found fatty dystrophy of the pancreas. And not only in people with excess weight, but also in skinny. I was buried there that it was not scary, but now I think. What is worth taking this pathology more seriously. Although the disease is chronic. But you can delay its manifestation for many years. It is important to eat right and not abuse alcohol.
Such changes in the state of the pancreas can develop with the right lifestyle. This provoking factor can serve as complications after illness, as well as intoxication after poisoning.
Causes of lipomatosis
What is lipomatosis and what does the appearing entry in the epicrisis of a sick-list mean - pancreatic lipomatosis? Such a diagnosis is made only when the development of fat and pathogenic cells that change the healthy environment of the pancreas and its cellular composition is detected in the internal organs of the body. This happens at the moment when the metabolism is disturbed, which leads to glandular dystrophy.
The appearance process will be generalized or regional. The nature of the development of changes that occur in the pancreas, have their own forms of transformation:
- knotted transform
- developed diffuse,
- diffuse nodular compaction.
In the first form of the pathology, nodes appear in the capsule. They have a group location and a symmetrical state.
At the moment of diffusion, the pathology progresses in the subcutaneous tissue with abundant fat and in the inner part of the pancreas. Perhaps the manifestation of muscle lipoma, which grows in the immediate vicinity of the muscle fibers and not having clearly defined boundaries.
Diffuse-nodular form of pathology, characterized by two simultaneously progressive pathologies with the growth of adipose tissue. The development of lipomatosis, a pathology that has not yet been studied, and the causes of its manifestation are associated with a failure in metabolism and exposure to catecholamines.
It is often observed that the occurrence of this pathology creates problems with the liver, pancreas, thyroid and is accompanied by a violation of the pituitary gland.
In some cases, lipomatosis manifests itself from the abundant use of alcohol, diabetes, congenital heredity. The disease also becomes a consequence of oncological diseases and an increased content of urea in the blood of the affected person.
Each process in the human body does not occur independently. Therefore, whatever the pathology with lipomatosis, they lead to the consequences of their development and aggravate the patient's condition. For example, in case of pancreatitis, the main development is diabetes, and this is the main disease of people with overweight. This is displayed on the state of the liver, which is detected only by the method of diagnosis of the pancreas organ.
Fatty infiltration in inflammatory processes of the pancreas, manifested in such cases:
- violation of dietary norms of nutrition,
- non-professional therapy of diseases.
The consequences of the pathology of lipomatosis, which lead to a complicated course of the disease, are especially exacerbated by obesity of the pancreas and the occurrence of serious malfunctions of the digestive system.
Diffuse change of the pancreas, which arose by the type of lipomatosis, involves the creation of focal fatty tumors over the entire area of the pancreas. This pathology for quite a long time does not make itself felt and does not cause damage to the tissues of the gland, and this does not create abnormalities in the work of the pancreas. Identify this problem in random order when diagnosing other diseases. Lipomatosis itself as a disease progresses slowly, then accelerating, then, on the contrary, stopping in its development, and can stay in this mode all its life without threatening the health of the sick person.
There are reasons for the development of the disease - lipomatosis:
- chronic negative processes of the pancreas,
- pancreas injury,
- developing diabetes
- harmful abuse of habits (smoking, alcohol, drug abuse),
The disease is lipomatosis, in childhood, is practically detected and does not progress, but is a risk for the elderly.
Symptoms of the disease
Often the pathology passes without the slightest signs and symptoms, manifesting which would force a person to undergo a complete examination of the pancreas. Everything is explained by the fact that pancreatic obesity occurs by islands throughout the body and at the initial stage of nucleation does not cause problems in the functioning of the gland. Just starting to progress and increase, the lipomatous focus begins to transform and show some symptoms of development. What are the primary signs and symptoms of lipomatosis:
- heaviness after eating in the stomach,
- pain in hypochondrium
- violation of stool (constipation, diarrhea),
- general weakness of the body
- increased fatigue.
Pathology is an irreversible process for the human body and brings the inability of the pancreas to perform its functional duties.
Basically, it occurs in inflammatory processes of the pancreas, when healthy cells die. Only in this case, fatty cells, which maintain the shape of the gland, but do not participate in its work and functions, are growing in place of the dead cells. In this case, the replacement process gets out of control with time, which leads to a strong increase in adipose tissue.
However, there are cases when the lipomatosis does not develop in large-scale volumes and values, since in the human body there is no predisposition and heredity to pathology. In the initial stage of the disease, the pancreatic lipomatosis, which belongs to the first stage of development, proceeds without visible changes and symptoms of the process. Therefore, the detection of pathology occurs late, which carries with it the complexity of treatment. Pancreatic obesity creates its own symptoms and this pathological condition requires urgent treatment.
Diffuse changes in lipomatosis
Lipomatosis of the gland is a serious disease due to its unpredictability. Formed in the gland, does not manifest itself until the moment most favorable for its development. There is a definition and kind of three degrees and types of lipomatosis:
- Lipomatosis of the pancreas, related to the 1 degree of development. The percentage of organ damage is up to 30%, the absence of symptoms of the disease, the work of the pancreas proceeds without visible changes.
- Lipomatosis of pancreatic 2nd degree and pathology. The defeat of the gland is from 30-60%. Manifesting symptoms speaks of gastrointestinal diseases and is accompanied by heartburn, severe abdominal distention, sour belching, intestinal upset.
- Grade 3 disease of lipomatosis. The defeat of the pancreas over 60%, a strong malfunction of the gastrointestinal tract, the production of enzymes is completely absent. The most serious pathologies begin to progress (diabetes mellitus, dry skin, a sharp decrease in the patient’s body weight).
There are certain signs by which diffuse changes in the gland can be recognized. For this look at the signs:
- dryness in the mouth,
- strong belching with a taste of rotting food,
- ulcers on the mucous membrane of the oral cavity.
The brightest signs and symptoms appear depending on the cause of the development of this pathology.
Fatty infiltration of the liver and pancreas, is a direct evidence of metabolic disorders in the body of a sick person. Increasing fatty tissue causes the organs to dysfunction of their duties. The most susceptible to this disease, lovers of strong alcoholic products, with the development of chronic or acute pancreatitis.
Diagnosis of the disease
Diagnosis of the disease takes place on the analysis of the course of the disease, manifested chronic diseases, data obtained by ultrasound of the peritoneum. Full information provides ultrasound, which allows more fully identify the affected areas and assess the condition of the gland. The fat that has arisen on the pancreas, produces at the time of the diagnosis of ultrasound, the return of uneven echo, which tells about its accumulation and size on the body of the pancreas organ. So the diagnosis becomes clear and the definition of the disease occurs.
But this type of diagnosis requires confirmation, as fatty degeneration, similar to the obtained ultrasound data with other dangerous diseases such as necrosis or cancer of the pancreas.
Diet important stage of therapy
Pancreatic obesity requires adherence to dietary intake. The main thing for this is the Table No5 and No5п. These numbers of dietary food intake are major for diseases of the gastrointestinal tract and pancreatitis of all types and forms of pathology.
These methods reduce the load on the pancreas and reduce lipoproteins and cholesterol, which gives the moment the relief of the formation of adipose tissue and cells. It helps people with excess weight, as it is the most brutal diet for this pathology. Since the restoration of damaged cells of the body is not possible, the main task is to stop the development of the disease.
A diet with lipomatosis and inflammation of the pancreas is the main and decisive factor in the treatment of the disease, and in the system with traditional methods of treatment and medicamental help for pathology it will increase the chances of longevity.
Prognosis and prevention
Fatty infiltration of pancreatic tissue, develops due to malnutrition, abuse of bad habits. In addition, the pushing factors for the development of lipomatosis are:
- lack of body movements sufficient for the human body,
- heart disease, kidney, liver,
- harmful food.
Only by removing the accompanying causes of the pathology, does the development of a pancreatic lipomatosis develop. It is welcomed once a year, or even half a year, they will be checked and undergo a full diagnostic cycle, which will enable the treatment of a developing disease - lipomatosis.